Steroid responsive anti-Hu-associated paraneoplastic encephalitis with bilateral frontal lobe lesions
نویسندگان
چکیده
منابع مشابه
An unusual presentation of anti-Hu-associated paraneoplastic limbic encephalitis.
Paraneoplastic limbic encephalitis is a rare disorder characterized by personality changes, seizures, memory loss, and psychiatric symptoms often associated with antineuronal antibodies. It is well described in the adult literature but is still underreported in the pediatric literature. Symptoms are usually multifocal and subacute in presentation, occurring over days to weeks; however, in rare ...
متن کاملParaneoplastic syndromes associated with anti-Hu antibodies.
Paraneoplastic syndromes are disorders associated with cancer but without a direct effect of the tumor mass or its metastases on the nervous system. Small cell carcinoma of lung associated with paraneoplastic sensory neuronopathy and/or paraneoplastic encephalomyelitis with the presence of anti-Hu antibodies has been termed "anti-Hu syndrome." Anti-Hu associated PSN-PEM is an immune disorder in...
متن کاملImmunopathogenesis of paraneoplastic neurological syndromes associated with anti-Hu antibodies
Paraneoplastic neurological disorders (PNDs) are syndromes that develop in cancer patients when an efficient antitumor immune response, directed against antigens expressed by both malignant cells and healthy neurons, damages the nervous system. Herein, we analyze existing data on the mechanisms of loss of self tolerance and nervous tissue damage that underpin one of the most frequent PNDs, the ...
متن کاملAnti-Ma2 Paraneoplastic Encephalitis Associated with Ileal Lymphoma
A 62‐year‐old male with a history of hypertension and diabetes mellitus presented with 6 months of mental and behavior change. He had memory loss and visual hallucinations since September 2013. The patient gained 12.5 kg of bodyweight increase due to increased appetite and was diagnosed as bulimia nervosa at a local hospital. He also stated dizziness, unstable walking and diplopia with ptosis o...
متن کاملIntrathecal synthesis of anti-Hu antibodies distinguishes patients with paraneoplastic peripheral neuropathy and encephalitis
BACKGROUND Paraneoplastic syndromes are serious immune caused diseases of the peripheral and/or central nervous system associated with malignant neoplasm. Symptoms develop when antibodies against antigens expressed by tumor cells cross-react with neuronal proteins. Antineuronal antibodies are usually examined in patient's sera while examination of the cerebrospinal fluid (CSF) often fails. Furt...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Rinsho Shinkeigaku
سال: 2013
ISSN: 0009-918X,1882-0654
DOI: 10.5692/clinicalneurol.53.273